

Using it on Carrion Queen, Chub, or C.H.A.D.Using it on Grubs will instantly kill them.Using it on Loki will turn him into Lokii.Gemini will immediately separate in two, resulting in Suture being enraged even if no damage has been dealt otherwise.If used enough times, Delirium will die.Unlike other enemies, Delirium has no limit on how many times it can be split with Meat Cleaver.Mom's Heart, It Lives, Isaac, Error: Error: The given entity ("Satan") does not exist., ?, The Lamb, Mega Satan, Hush, Ultra Greed, Mother, Dogma, Ultra Famine, Ultra Pestilence, Ultra War, Ultra Death, and The Beast cannot be split.Multi-segmented enemies will only take damage on one segment.Invincible enemies, such as Stone Grimaces and lowered Hosts, will not be split.Maws specifically will be left with just their head.

If the enemy has a cable between them, such as Mr.There are several exceptions listed in the notes section. or Buttlickers, they will have their segments cut down to half, rounding down. If the enemy has segments, such as Larry Jr.If the enemy splits as part of their mechanic, such as Squirt, Teratoma, or The Fallen, they will instead take the damage required to split them.If an enemy cannot be split, they instead take 25 damage. Normal enemies can be split twice, while champions and bosses can be split three times.Upon use, splits enemies in the room into two smaller versions with ~40% health each.
